L-Azetidine-2-carboxylic acid,the antidermatophyte constituent of two marine sponges |
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Authors: | B. Bach R. P. Gregson G. S. Holland R. J. Quinn J. L. Reichelt |
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Affiliation: | (1) Microbiology Section and Chemistry Section, Roche Research Institute of Marine Pharmacology, P.O. Box 255, 2099 Dee Why, N.S.W., Australia |
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Abstract: | Summary The aqueous ethanolic extract of 2 related marine spongesHaliclona sp. andChalinopsilla sp. displayed antidermatophyte activities specific forTrichophyton mentagrophytes. The active consituent of both sponges was isolated and shown to be L-azetidine-2-carboxylic acid. |
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