Increased activity of the ribosomal dissociation factor in the pre-replicative phase of liver regeneration after partial hepatectomy |
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Authors: | R Comolli A Schubert M Cojazzi L Riboni |
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Institution: | (1) Centro di Studio per la Patologia cellulare del C.N.R., via Mangiagalli, 31, I-20133 Milano, (Italy);(2) Istituto di Patologia generale, Università di Milano, via Mangiagalli, 31, I-20133 Milano, (Italy) |
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Abstract: | Summary The activity of the ribosomal dissociation factor and the formation in vitro of free 60S and 40S subunits increased in the first 12–48 h after partial hepatectomy. This suggests an, accelerated reconversion into active subunits of ribosomes that complete a translation cycle in the early phases of liver regeneration.The technical assistance of Miss M. Ravazzani and Miss L. zingaretti is gratefully acknowledged. |
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