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Multiple intron gain and loss events occurred during the evolution of Cenp-A gene |
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| Authors: | XinYu Fan Li Yu HuaiLiang Xu Ying Li |
| Institution: | 15623. College of Animal Science and Technology, Sichuan Agricultural University, Ya’an, 625014, China 25623. Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming, 650091, China 35623. Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, 650091, China 45623. Institute of Animal Breeding and Genetics, Sichuan Agricultural University, Ya’an, 625014, China |
| Abstract: | Centromere protein A (CENP-A) is a histone H3 like protein, and it plays a very important role in chromosomal segregation during mitosis and meiosis. The analyses on the exon-intron organization of the Cenp-A gene in representative genomes revealed that multiple intron gain and loss events have occurred during the evolution of Cenp-A gene in opisthokonta (common ancestor of fungi and animals). Moreover, our results revealed that at least two positions were conserved in the intron gain and loss events during the evolution of the Cenp-A gene. |
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