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DNA methylation in chicken brain and liver
Authors:R Harasawa  T Mitsuoka
Institution:(1) The Institute of Physical and Chemical Research, 351 Wako, Saitama, (Japan);(2) Faculty of Agriculture, University of Tokyo, 113 Bunkyo, Tokyo, (Japan);(3) Present address: School of Veterinary Medicine, Miyazaki University, 880 Miyazaki, Japan
Abstract:Summary Adult chicken brain DNA is subject to a developmental alteration of methylation atHpaII sites flanking 4, 1, 0.8 and 0.7 kilobase sequences. This change is not evident in adult chicken liver DNA and 1-day-old chick brain and liver DNAs, suggesting tissue specificity and age-dependency in DNA methylation.
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