一种含有1,2,3-三氮唑基团的罗丹明B衍生物的合成及其金属离子响应

将2-苯基-5-三氟甲基-2H-1,2,3-三氮唑-4-羧酸乙酯(Ethyl 2-phenyl-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylate,简称PTCT)作为反应物,设计与罗丹明B合成了一种新型含有1,2,3-三氮唑基团的罗丹明B化合物.通过核磁共振、高分辨质谱对其结构进行了表征;并应用紫外吸收和荧光分析法研究了此衍生物与15种金属离子的作用.结果表明:在一定浓度范围内,DMF(N,N-二甲基甲酰胺)-水溶液中(p H 7.4),该化合物对Hg~(2+)的特异响应比其他离子灵敏,使其荧光增强,并且反应时间很快.用等摩尔连续变化法测定其与Hg~(2+)的络合比为1∶2,研究结果可为进一步开发利用此类三氮唑化合物提供科学合理的理论指导.

The Synthesis and Metal Ions Responses of RhodamineB Derivatives Containing 1 ,2 ,3 - Triazole

A novel Rhodamine B derivative containing 1 ,2 ,3 - triazole was synthesized by the reaction between RhodamineB and ethyl 2 - phenyl - 5 - ( trifluoromethyl) - 2H - 1 ,2, 3 - triazole - 4 - carboxylate (PfCT ) . The corresponding productwas characterized by NMR and HRESIMS methods. The interactions of the compound with 15 kinds of metal ions wereinvestigated by UV absorption spectra and fluorescence spectra. It displayed more sensitive response to Hg2+ ion than othermetal ions in N, N - DimethylformaIllide (DMF) - water ( V( DMF) : V( H2 0 ) =1 : 1 , pH 7. 4) under given conditionswith an fluorescent enhancement and a rapid chemical reaction. The 1 : 2 of stoichiometric structure of RPfCT and Hg2+was confirmed using a Job'' s plot estimation. The result can provide some scientific and reasonable theoretical guidance forthe further exploitation and utilization of these 1 ,2 ,3 - trizoles.