| Visualization of Gene Mutation Complicated Pattern of Hepatitis B Virus Based on Cellular Automata |
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| 作者姓名： | 邵世煌 肖绚 丁永生 黄振德 |
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| 作者单位： | [1]CollegeofInformationScience＆Technology,DonghuaUniversity,Shanghai200051 [2]CollegeofInformationScience＆Technology,DonghuaUniversity,Shanghai200051／／DepartmentofMechanicalandElectrical,JingdezhenCeramicInstitute,Jingdezheng333001 |
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| 基金项目： | Doctoral Foundation from National Education Committee (20030255009), P. R.China |
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| 摘 要： | Hepatitis B virus shows instantaneous and high rate mutations in biological experiments, some sorts of which affect the efficiency of virus replication greatly through enhancing or depressing the viral replication, while others have no influence at all. Taking advantage of prominent features of cellular automata, we simulate the effect of hepatitis B virus gene mutation on its replication efficiency. The computer simulation results demonstrate the feasibility of our novel model by comparing with the results of biological experiments.
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| 关 键 词： | 基因突变 肝炎病毒 细胞 乙型肝炎 人体 |
Visualization of Gene Mutation Complicated Pattern of Hepatitis B Virus Based on Cellular Automata |
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| SHAO Shi-huang,Xiao Xuan,DING Yong-sheng,HUANG Zhen-de.Visualization of Gene Mutation Complicated Pattern of Hepatitis B Virus Based on Cellular Automata[J].Journal of Donghua University,2005,22(1):60-63. |
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| Authors: | SHAO Shi-huang Xiao Xuan DING Yong-sheng HUANG Zhen-de |
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| Abstract: | Hepatitis B virus shows instantaneous and high rate mutations in biological experiments, some sorts of which affect the efficiency of virus replication greatly through enhancing or depressing the viral replication, while others have no influence at all. Taking advantage of prominent features of cellular automata, we simulate the effect of hepatitis B virus gene mutation on its replication efficiency. The computer simulation results demonstrate the feasibility of our novel model by comparing with the results of biological experiments. |
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| Keywords: | Hepatitis B Virus Gene Mutation Virus Replication Cellular Automata |
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