Effects of increased ambient CO2 levels on human and animal health

This is the last work to have been completed by Karl Ernst Schaefer, who died on December 26th 1981, in Old Lyme, Connecticut. The physiological changes and problems brought on by an excess of carbon dioxide was, for many years, one of the prime research interests of this eminent respiratory physiologist. In the present work, Schaefer explored the physiological limits of diving with varying N₂–O₂ mixtures. The paper contains a wealth of information relevant to the many still unanswered questions in the field and invaluable suggestions with respect to the course of future research. This work yielded, moreover, some interesting disease models for such disturbances as arrhythmia and bradycardia.