| 福美双对斑马鱼胚胎心脏发育的影响 |
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| 引用本文： | 于永利,李慧蕾,王亚臣,乔新国. 福美双对斑马鱼胚胎心脏发育的影响[J]. 内蒙古民族大学学报(自然科学版), 2011, 26(3) |
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| 作者姓名： | 于永利 李慧蕾 王亚臣 乔新国 |
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| 作者单位： | 1. 内蒙古民族大学,内蒙古,通辽,028000
2. 通辽市早繁鱼苗试验厂,内蒙古,通辽,028000 |
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| 摘 要： | 福美双是我国使用非常广泛、生产量非常大的一种高残留农药,福美双的毒性与高残留性逐步引起世界各国的重视.本研究使用斑马鱼作为实验动物模型,研究了福美双的毒性机制.结果表明福美双引起心囊水肿等外观形态学的变化,心囊水肿率与福美双的浓度呈正相关,通过组织切片进一步证实其致畸性变化.研究表明斑马鱼早期胚胎作为农药的生物学评价具有一定的参考价值.
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| 关 键 词： | 福美双 斑马鱼 心囊水肿 |
The Effect of Thiram on Heart Development of Zebrafish Embryos |
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| YU Yong-li,LI Hui-lei,WANG Ya-chen,QIAO Xin-guo. The Effect of Thiram on Heart Development of Zebrafish Embryos[J]. Journal of Inner Mongolia University for the Nationalities(Natural Sciences), 2011, 26(3) |
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| Authors: | YU Yong-li LI Hui-lei WANG Ya-chen QIAO Xin-guo |
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| Affiliation: | YU Yong-li~1,LI Hui-lei~1,WANG Ya-chen~2,QIAO Xin-guo~2 (1.Inner Mongolia University for Nationalities,TongLiao,028000,China,2.Tongliao Experimental Base Species Breeding,Tongliao 028000,china) |
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| Abstract: | Thiram is one of the mass produced and widely used pesticides in China.The toxicity of Thiram and its high accumulation in organisms have been taken attention by many countries.We used zebrafish as an experimental animal model to study the mechanism of Thiram toxicity.As results,Thiram caused mophological changes including pericardio edema,Pericardial edema rate was positively correlated with the concentration of thiram,further confirmed by tissue section changes of its teratogenicity.This study indicated t... |
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| Keywords: | Thiram Zebrafish Pericardial edema |
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