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| 多糖的分子修饰研究进展 | |
| 引用本文： | 张难,吴远根,莫莉萍,张永凤,邱树毅,王文平.多糖的分子修饰研究进展[J].贵州科学,2008,26(3). |
| 作者姓名： | 张难 吴远根 莫莉萍 张永凤 邱树毅 王文平 |
| 作者单位： | 1. 贵州省发酵工程与生物制药重点实验窒,贵州,贵阳,550003;贵州大学生命科学学院,贵州贵阳,550025 2. 贵州省发酵工程与生物制药重点实验窒,贵州,贵阳,550003;贵州大学化学工程学院,贵州,贵阳,550003 3. 贵阳市生产力促进中心,贵州,贵阳550002 4. 贵州省发酵工程与生物制药重点实验窒,贵州,贵阳,550003 |
| 基金项目： | 贵州省优秀科教人才省长基金;;贵州省自然科学基金(基合字(1999)3105) |
| 摘 要： | 多糖是重要的药用活性成分,具有抗肿瘤、抗凝血和免疫调节活性等多种功能,而多糖的分子修饰能够提高它原有的活性或增加新的活性.本文详细阐述了多糖的硫酸化、磷酸化、乙酰化等分子修饰及其对生物活性的影响,最后对多糖的分子修饰及其应用进行了展望. |
| 关 键 词： | 多糖 分子修饰 生物活性 |
PROGERSS IN MOLECULAR MODIFICATION OF POLYSAC-CHARIDES |
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| ZHANG Nan,WU Yuan-Gen,MO Li-Ping,ZHANG Yong-Feng,QIU Shu-Yi,WANG Wen-Ping.PROGERSS IN MOLECULAR MODIFICATION OF POLYSAC-CHARIDES[J].Guizhou Science,2008,26(3). | |
| Authors: | ZHANG Nan WU Yuan-Gen MO Li-Ping ZHANG Yong-Feng QIU Shu-Yi WANG Wen-Ping |
| Institution: | 1.Guizhou Key Laboratory of Fermentation Engineering and Biopharmacy;Guiyang 550003;2.College of Life Science;Guizhou University;Guiyang 550025;3.School of Chemical Engineering;4.Guiyang Productivity Promotion Center;Guiyang 550002 |
| Abstract: | Polysaccharides are the important medicine ingredient,which play significant role in anti-tumor,immunity modulation and anticoagulation.The structural modification of polysaccharides can not only enhance their intrinsic activities,but also increase the undiscovered activities.In this paper,the methods of structural modification such as sulfation,phosphorylation and acylation in polysaccharides and their influence on biological activity are introduced,and then the structural modification and application of p... |
| Keywords: | polysaccharide molecular modification biological activities |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |