| 新型水溶性抑菌剂咪唑季铵型反丁烯二酸单辛酯的合成及其抑菌活性研究 |
| |
| 引用本文： | 陈素艳,;宋凌生,;周常义,;欧光南.新型水溶性抑菌剂咪唑季铵型反丁烯二酸单辛酯的合成及其抑菌活性研究[J].漳州师院学报,2008(2):78-82. |
| |
| 作者姓名： | 陈素艳 ;宋凌生 ;周常义 ;欧光南 |
| |
| 作者单位： | [1]集美大学生物工程学院,福建厦门361021 |
| |
| 基金项目： | 福建省自然科学基金计划资助项目（U0650018）;厦门市科技项目（3502Z20073027） |
| |
| 摘 要： | 设计、合成并表征了新型水溶性抑菌剂咪唑季铵型反丁烯二酸单辛酯．采用光电比浊法、平板法和抑菌圈法测定咪唑季铵型反丁烯二酸单辛酯对细菌、霉菌、酵母的抑菌效果．结果表明，咪唑季铵型反丁烯二酸单辛酯具有较强的抑菌活性，且效果优于山梨酸和苯甲酸．碱性环境中，咪唑季铵型反丁烯二酸单辛酯抑菌活性较强．
|
| 关 键 词： | 合成 咪唑季铵型反丁烯二酸单辛酯 抑菌活性 |
Synthesis and Antimicrobial Activity of 1,3-dialkyl-imidazolium-based Trans-but-2-enedioic Acid Monooctyl Ester |
| |
| Institution: | CHEN Su-yan, SONG Ling-sheng, ZHOU Chang-yi, OU Guang-nan (School of Bioengineering, Jimei University, Xiamen, Fujian 361021, China) |
| |
| Abstract: | 1,3-dialkyl-imidazolium-based trans-but-2-enedioic acid monooctyl esters （RMIM]OFE]） were synthesized and characterized by NMR. All the characterization data are consistent with the theoretic compositions and structures. Antimicrobial activity against bacteria, streptomyces, and yeast were systematically studied by the photoelectricity turbidimetric method, spread-plate method, and zone of inhibition method. In contrast with benzoic acid and sorbic acid, the results of antimicrobial activity of RMIM]OFE] could remarkably inhibit those microbial. Effect of pH on antimicrobial activity of RMIM]OFE] was remarkable, which strongest inhibition ability was obtained in the alkaline environment. |
| |
| Keywords: | synthesis 1 3-dialkyl-imidazolium-based trans-but-2-enedioic acid monooctyl ester antimicrobial activity |
| 本文献已被 维普 等数据库收录！ |
|
