Preparation of Electrospun CdSe-Quantum-Dots-Doped Porous Films |
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Authors: | GAO Bing SHEN Chao YUAN Shuang-long ZHANG Jian-guang YANG Yun-xia MO Xiu-mei LI Hai-yan |
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Institution: | 1. Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China 2. College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, China 3. Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiaotong University, Shanghai 200030, China |
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Abstract: | Electrospun porous films doped with the green-synthesized CdS e quantum dots were synthesized.Glycerol was chosen to prepare the quantum dots( QDs),with the highest quantum yield of 78.28%.Polycaprolactone( PCL) was electrospun with CdS e QDs to avoid the QDs' toxicity and improve the QDs' cytocompatibility.The electrospun QDs-doped films preserve the original QDs' fluorescence.Pores can be detected from the SEM of the films,predicting the possibility of loading drugs in the cancer therapy.The cell proliferation assay shows excellent cytocompatibility of the eletrospun CdS e-QDs-doped films.The present eletrospun CdS eQDs-doped porous films are cytocompatibale,highly-fluorescent and potential to load drugs in cancer therapy. |
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Keywords: | CdSe quantum dots (QDs) electrospun films polycaprolactone (PCL) photoluminescence (PL) cytocompatibility cell proliferation assay |
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