Autophagy and lysosomal proteolysis in the liver |
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Authors: | B. Grinde |
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Affiliation: | (1) Department of Biology, Division of Zoology, University of Oslo, Blindern, P.O. Box 1050, 0316 Oslo 3, (Norway) |
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Abstract: | Summary Autophagy is defined as any process whereby cellular macromolecules destined for degradation gain access to the lysosomes. A review is presented on the physiological significance, mechanisms and regulation of autophagy in hepatocytes, concentrating on the issue of regulation. The article ends by discussing techniques available for future research. |
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Keywords: | Autophagy hepatocytes protein degradation lysosomes |
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