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Autophagy and lysosomal proteolysis in the liver
Authors:B. Grinde
Affiliation:(1) Department of Biology, Division of Zoology, University of Oslo, Blindern, P.O. Box 1050, 0316 Oslo 3, (Norway)
Abstract:Summary Autophagy is defined as any process whereby cellular macromolecules destined for degradation gain access to the lysosomes. A review is presented on the physiological significance, mechanisms and regulation of autophagy in hepatocytes, concentrating on the issue of regulation. The article ends by discussing techniques available for future research.
Keywords:Autophagy  hepatocytes  protein degradation  lysosomes
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