双酚A分子印迹聚合物的制备及其在环境监测中的应用初探

采用分子印迹技术,以双酚A为模板分子、2-乙烯吡啶为功能单体,通过微球法合成了对双酚A具有高度选择性的分子印迹聚合物(MIPs),以此印迹聚合物为固相萃取填料,试验了聚合物在结构相似底物竞争环境下对双酚A的特异选择性能.通过Scatchard分析,该聚合物对双酚A存在两类不同的结合位点,其中特异性结合的平衡常数达1.78×105 L/mol,表观最大吸附量为7.23μmol/g.固相萃取结果表明:合成的MIPs对双酚A具有高度的特异选择性,为从复杂环境介质中分离富集双酚A提供了一种快速有效的方法.

The Preparation of Bisphenol A Molecularly Imprinted Polymers and Its Pilot Application in Environmental Monitoring

By using molecularly imprinted technology(MIT),molecularly imprinted nano-polymers was prepared from Bisphenol A(BPA) as the template molecules,2-vinylpyridine as the functional monomer.Its adsorption property was evaluated by batch adsorption experiments,and the selectivity of the polymers for substrate was investigated by solid-phase extraction column packed with the molecularly imprinted polymers.The results showed that the polymers exhibited high affinity for BPA and good selectivity among the tested compounds.Scatchard analysis demonstrated that two different classes of the binding sites were formed in imprinted polymer which had different affinity to BPA.The favorable association constant for BPA binding to be KB =1.78×105 L / mol.Density of the BPA-specific receptor sites in the MIP material was 7.23 μmol / g.It indicated that this was a new way for the selective separation,enrichment and determination of trace BPA in complex biosamples.