| 人LAK及LI-LAK细胞对S_(180)荷瘤小鼠的治疗作用 |
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| 引用本文： | 钟瑜,张春雪,谢琪璇,潘善培,刘学高.人LAK及LI-LAK细胞对S_(180)荷瘤小鼠的治疗作用[J].暨南大学学报,1998(Z1). |
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| 作者姓名： | 钟瑜 张春雪 谢琪璇 潘善培 刘学高 |
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| 作者单位： | 暨南大学生殖免疫研究中心!广州，510632 |
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| 摘 要： | 用LAK和LI－LAK两种细胞进行S180荷瘤小鼠体内抗肿瘤试验。结果表明，人LAK细胞及LI－LAK细胞有明显的体内抗S180肉瘤作用，S180荷瘤鼠存活期显著延长，其平均存活时间分别为45．3和49．6d，且部分可完全治愈；而未用药的对照组鼠只平均存活21.1d，仅用IL－2治疗的荷瘤鼠平均存活时间为35．9d。同时可知，两实验组中两种细胞作用程度相差不大（P＞0．05）。
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| 关 键 词： | 人LAK细胞 人LI－LAK细胞 白细胞介素2 S_（180）肉瘤 |
Using Human LAK and LI - LAK Cells to Cure S_(180) Tumor Bearing Mice |
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| Zhong Yu, Zhang Chunxue, Xie Qixuan, Pan Shanpei, liu Xuegao.Using Human LAK and LI - LAK Cells to Cure S_(180) Tumor Bearing Mice[J].Journal of Jinan University(Natural Science & Medicine Edition),1998(Z1). |
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| Authors: | Zhong Yu Zhang Chunxue Xie Qixuan Pan Shanpei liu Xuegao |
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| Abstract: | In this experiment, we used murine S180 tumor as target to examine the antitumor effects in vivo of human LAK and LI- LAK cells. The results showed that the human LAK and LI- LAK cells could mediate S180.tumor cell lysis in vivo and prolong the survival time of tumor beating mice, their average survival time were 45. 3 d and 49. 6 d respectively. Some of them could be cured, and there were no significant different between two kinds of cells about the ability of antitumor(P > 0. 05). |
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| Keywords: | human LAK cell Human LI- LAK cells IL - 2 S_(180) tumor |
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