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Multiple newly identified loci associated with prostate cancer susceptibility |
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| Authors: | Eeles Rosalind A Kote-Jarai Zsofia Giles Graham G Olama Ali Amin Al Guy Michelle Jugurnauth Sarah K Mulholland Shani Leongamornlert Daniel A Edwards Stephen M Morrison Jonathan Field Helen I Southey Melissa C Severi Gianluca Donovan Jenny L Hamdy Freddie C Dearnaley David P Muir Kenneth R Smith Charmaine Bagnato Melisa Ardern-Jones Audrey T Hall Amanda L O'Brien Lynne T Gehr-Swain Beatrice N Wilkinson Rosemary A Cox Angie Lewis Sarah Brown Paul M Jhavar Sameer G Tymrakiewicz Malgorzata Lophatananon Artitaya |
| Institution: | The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK. rosalind.eeles@icr.ac.uk |
| Abstract: | Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common alleles associated with prostate cancer risk, we conducted a genome-wide association study (GWAS) using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at |
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