Pharmacological studies of a new analgesic,dl-erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride,in experimental animals |
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| Authors: | H Nakamura K Ishii Y Yokoyama S Motoyoshi C Imazu M Shimizu |
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| Institution: | (1) Department of Pharmacology, Research Laboratories, Dainippon Pharmaceutical Co., Ltd, 564 Suita, Osaka, Japan |
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| Abstract: | Summary dl-Erythro-1-phenyl-2-(o-chlorophenyl)-2-4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride showed orally a definite analgesic activity, without producing the significant morphine-like physical dependence liability, and its analgesic potency was about a half that of codeine and far superior to aminopyrine in experimental animals. |
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