A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin,toxins fromPenicillium islandicum Sopp |
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| Authors: | A. C. Ghosh A. Manmade A. Bousquet J. M. Townsend A. L. Demain |
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| Affiliation: | (1) SISA Inc., and Sheehan Institute for Research, Inc., 02138 Cambridge, Massachusetts, USA;(2) Department of Nutrition and Food Science, Massachusetts Institute of Technology, 02139 Cambridge, Massachusetts, USA |
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| Abstract: | Summary A rapid, convenient TLC method is described for detection of cyclochlorotine, a carcinogen produced by the commonly found storage moldPenicillium islandicum Sopp. This method has also led to the isolation of a new toxic metabolite, simatoxin.Acknowledgment. This work was supported by Food and Drug Administration, Washington, D.C. (Contract No. FDA-223-74-2209). |
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