| 基质金属蛋白酶家族在哺乳动物生殖过程中的作用 |
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| 引用本文： | 毛居戴·亚力,欧尔比特·安尼瓦尔,阿依古丽·沙帕尔.基质金属蛋白酶家族在哺乳动物生殖过程中的作用[J].新疆师范大学学报(自然科学版),1999(4). |
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| 作者姓名： | 毛居戴·亚力 欧尔比特·安尼瓦尔 阿依古丽·沙帕尔 |
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| 作者单位： | 新疆师范大学生物系 乌鲁木齐830054 |
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| 摘 要： | 在成年灵长类的生活中,生殖器官在结构和功能特性上都在发生着明显的变化。这些由激素控制,并受到局部生长因子和细胞因子调节的变化,都广泛存在着结缔组织的重组。结缔组织的重组需要ECM(细胞外基质)成份的降解和重新合成两个过程。有许多酶可以ECM蛋白质的降解,但基质金属蛋白酶(MMPs)被认为是这一过程中起主要作用的酶。本文对MMP家族做一简要综述后,将着重讨论MMPs在不同生理状态(月经周期,着床,妊娠与分娩)下子宫中的表达及调控。
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| 关 键 词： | 基质金属蛋白酶 子宫 表达 |
EFFCT OF MMPs IN REPRODUCTIVE PROCESS OF MAMMAL |
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| Mawjuda. Yali,Orbit. Anwar,Ayigue. Sapar.EFFCT OF MMPs IN REPRODUCTIVE PROCESS OF MAMMAL[J].Journal of Xinjiang Normal University(Natural Sciences Edition),1999(4). |
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| Authors: | Mawjuda Yali Orbit Anwar Ayigue Sapar |
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| Abstract: | Throughout adult primates' life, the reproduction organs change distinctively in their structure and functional properties. The changes controled by hormone and mediated by partial growth factors and cytokines involve extensive reformation of connective tissues. The reformation of connective tissues requires both degradation and resysthe-sis of ECM components. The degradation of ECM proteins can be effected by a variety of enzymatic activities,but the Matrix metalloproteinases(MMPs)are believed to be primary contributors to this process. Following a brief sammary of the MMP family,the paper emphatically discusses the expression patterns of MMPs in the uterus in different physiological states. |
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| Keywords: | MMPs Uterus Expression |
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