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Inhibition of mouse liver protein and nuclear RNA synthesis following combined oral treatment with sodium nitrite and dimethylamine or methylbenzylamine |
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| Authors: | M A Friedman G Millar M Sengupta S Epstein |
| Institution: | (1) Laboratories of Environmental Toxicology and Carcinogenesis, Children's Cancer Research Foundation Inc., 02115 Boston, Massachusetts, USA;(2) Department of Pathology, Harvard Medical School, 02115 Boston, Massachusetts, USA;(3) Present address: Swetland Professor of Environmental Health and Human Ecology, Case Western Reserve University Medical School, 44106 Cleveland, Ohio, USA |
| Abstract: | Zusammenfassung Orale Gabe von Dimethylamin oder Methylbenzylamin zusammen mit Natriumnitrit bewirkte eine synergistische Hemmung der Protein-Synthese in der Leber von Mäusen. Ausserdem hemmte die kombinierte Gabe von Dimethylamin und Nitrit synergistisch die Synthese nuklearer RNS in der Leber. Supported by N.I.H. Grants No. C-6516 and No. FR-05526. |
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