| 不同pH值对京尼平交联胶原制备生物材料的影响 |
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| 引用本文： | 汪红,苏建,高陪,沈竞,孙启玲.不同pH值对京尼平交联胶原制备生物材料的影响[J].四川大学学报(自然科学版),2011,48(2):481-485. |
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| 作者姓名： | 汪红 苏建 高陪 沈竞 孙启玲 |
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| 作者单位： | 四川大学生命科学院生物资源与生态环境教育部重点实验室,成都,610064 |
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| 基金项目： | 成都市科技局项目(2GGYB017NC-010) |
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| 摘 要： | 通过测定京尼平交联胶原后的颜色、交联度、吸液率、降解率及细胞毒性的变化, 研究交联pH值对京尼平交联胶原制备生物材料的影响.分别于pH5.0，5.5，6.0，6.5，7.0条件下, 在0.5%京尼平水溶液中交联24 h，以未交联的胶原作为对照, 评价所得材料的颜色、交联度、吸液率、降解率、细胞毒性及组织相容性特点.当pH为5.5时, 交联后材料的颜色较浅, 且较好的生物相容性以及良好的抗降解性.
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| 关 键 词： | 京尼平 胶原 交联反应 |
Effect of pH on crosslinking of collagen with genipin |
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| WANG Hong,SU Jian,GAO Pei,SHEN Jing and SUN qi-Ling.Effect of pH on crosslinking of collagen with genipin[J].Journal of Sichuan University (Natural Science Edition),2011,48(2):481-485. |
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| Authors: | WANG Hong SU Jian GAO Pei SHEN Jing and SUN qi-Ling |
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| Institution: | Key Laboratory of Bio-resources and Eco-environment of Ministry of Education,College of Life Sciences, Sichuan University;Key Laboratory of Bio-resources and Eco-environment of Ministry of Education,College of Life Sciences, Sichuan University;Key Laboratory of Bio-resources and Eco-environment of Ministry of Education,College of Life Sciences, Sichuan University;Key Laboratory of Bio-resources and Eco-environment of Ministry of Education,College of Life Sciences, Sichuan University;Key Laboratory of Bio-resources and Eco-environment of Ministry of Education,College of Life Sciences, Sichuan University |
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