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Selective blockade of components of potassium activation inMyxicola axons
Authors:M. A. Chuman  C. L. Schauf  F. A. Davis  D. Stefoski
Affiliation:(1) Dept of Physiology, Rush University, 1753 W. Congress Parkway, 60612 Chicago, Illinois, USA;(2) Dept of Biology, Purdue University School of Science, 1125 East 38th Street, 46223 Indianapolis, Indiana, USA;(3) Dept of Biology, IUPUI, 1125 East 38th Street, 46223 Indianapolis, Indiana, USA
Abstract:Summary The K+ conductance inMyxicola giant axons activates in two phases which are pharmacologically separable. The fast phase of K+ activation is specifically inhibited by 4-aminopyridine and by the substitution of D2O for H2O. We suggestMyxicola giant axons, like the amphibian node of Ranvier, may possess more than one variety of K+ channel.
Keywords:Potassium conductance  Myxicola axons  neuronal cell bodies  multiple K+ channels
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