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采用正交实验法优选泌炎康胶囊的提取工艺
引用本文:郑春英,平文祥,葛菁萍. 采用正交实验法优选泌炎康胶囊的提取工艺[J]. 哈尔滨商业大学学报(自然科学版), 2005, 21(3): 277-278
作者姓名:郑春英  平文祥  葛菁萍
作者单位:黑龙江大学,生命科学学院,黑龙江,哈尔滨,150080
基金项目:黑龙江省教育厅资助项目(No.80009).
摘    要:以绿原酸得率为指标,采用正交试验设计及高效液相法(HPLC)考察了影响泌炎康胶囊提取工艺的因素(A煎煮次数、B煎煮时间和C加水量).分析后确定影响泌炎康胶囊提取工艺的主要因素为A(煎煮次数)和B(煎煮时间),优选出最佳提取工艺为煎煮2次,每次加水12倍,煎煮1h.试验证明,该工艺合理可靠,提取效率较高。

关 键 词:泌炎康胶囊  正交试验  绿原酸
文章编号:1672-0946(2005)03-0277-02
修稿时间:2005-04-11

Study on extraction process for Miyankang capsules with orthogonal design
ZHENG Chun-ying,PING Wen-xiang,GE Jing-Ping. Study on extraction process for Miyankang capsules with orthogonal design[J]. Journal of Harbin University of Commerce :Natural Sciences Edition, 2005, 21(3): 277-278
Authors:ZHENG Chun-ying  PING Wen-xiang  GE Jing-Ping
Abstract:To explore the optimum extracting conditions for Miyankang Capsules, the content of Chlorogenic Acid was observed by method of orthogonal design and HPLC determination in order to optimize the influencing factors. boiling times A, boiling duration B and amount of water C. The results of analysis showed that the main influencing factors are A and B, and optimum extracting condition were adding twelve times amount of water and boiling and extracting for two times, one hour per time. The test verifies that the process is reasonable and reliable with higher extraction efficiency.
Keywords:Miyankang Capsules  orthogonal design  chlorogenic acid  
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