Synthesis of an analog of human calcitonin gene related peptide, [Asu2,7]-h-CGRP |
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| Authors: | T Noda K Morita T Uzawa H Kinoshita M Hori |
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| Institution: | (1) Research Laboratory, Toyo Jozo Co., Ltd., Ohito, Tagata, 410-23 Shizuoka, (Japan) |
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| Abstract: | Summary The analog of h-CGRP, des-Ala-deamino-dicarba-h-CGRP, was synthesized by the combination of the conventional solution and the solid phase peptide synthesis methods. This analog showed stronger and longer-lasting hypocalcemic and hypophosphatemic activities than the natural hormone.30 September 1986 |
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| Keywords: | h-CGRP analog synthesis Ca and Pi lowering effects |
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