| A generalized approach for protein design based on the relative entropy |
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| 引用本文： | WANGYihua WANGBaohan LIUYun CHENWeizu WANGCunxin. A generalized approach for protein design based on the relative entropy[J]. 科学通报(英文版), 2004, 49(5): 426-431. DOI: 10.1007/BF02900958 |
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| 作者姓名： | WANGYihua WANGBaohan LIUYun CHENWeizu WANGCunxin |
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| 作者单位： | [1]CollegeofLifeScienceandBioengineering,BeijingUniversityofTechnology,Beijing100022,China [2]InstituteofBiophysics（IBP）,ChineseAcademyofSciences,Beijing100101,China |
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| 摘 要： | In the present study, we have developed the method brought forward recently for protein design based on the relative entropy. The new approach can be used in more common situation other than the special limits in the anterior method. The results indicate that our generalized method has increased the prediction precision for protein sequence and will be in favor of the study for protein design.
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| 关 键 词： | 蛋白质设计 相对熵 逆蛋白展开 分子生物学 |
| 收稿时间： | 2003-12-02 |
A generalized approach for protein design based on the relative entropy |
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| Yihua Wang,Baohan Wang,Yun Liu,Weizu Chen,Cunxin Wang. A generalized approach for protein design based on the relative entropy[J]. Chinese science bulletin, 2004, 49(5): 426-431. DOI: 10.1007/BF02900958 |
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| Authors: | Yihua Wang Baohan Wang Yun Liu Weizu Chen Cunxin Wang |
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| Abstract: | In the present study, we have developed the method brought forward recently for protein design based on the relative entropy. The new approach can be used in more common situation other than the special limits in the anterior method. The results indicate that our generalized method has increased the prediction precision for protein sequence and will be in favor of the study for protein design. |
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| Keywords: | protein design relative entropy off-lattice model. |
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