Regulation of testosterone production in fetal testicular cells: effect of androgens |
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| Authors: | G Pointis M T Latreille L Cedard |
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| Institution: | (1) Groupe de Recherches sur l'Endocrinologie de la Reproduction, U. 166 INSERM, Maternité Port-Royal, 123, Bld Port-Royal, F-75014 Paris, France |
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| Abstract: | Summary Pre-incubation of dispersed testicular cells from 18-day-old mouse fetuses in presence of testosterone or dihydrotestosterone resulted in a significant decrease of the hCG-stimulated testosterone production. These results suggest that during late fetal life testosterone production may be inhibited by an ultra-short loop feedback of androgens. |
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