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| 细胞内圆柱形空间钙波的Fire-Diffuse-Fire模型 | |
| 引用本文： | 程玉,施小民,余宏旺,郑毓蕃.细胞内圆柱形空间钙波的Fire-Diffuse-Fire模型[J].上海大学学报(自然科学版),2010,16(1):68-74. |
| 作者姓名： | 程玉 施小民 余宏旺 郑毓蕃 |
| 作者单位： | 1. 上海大学理学院,上海,200444 2. 上海大学系统科学研究所,上海,200444 3. 上海大学理学院,上海,200444;华东师范大学数学系,上海,200062 |
| 摘 要： | 考察Fire-Diffuse-Fire模型在圆柱区域内钙波的传播情况.通过求解扩散方程,得到了圆柱区域内Ca2+浓度的解析表达式.分析证明了钙波的存在性、稳定性依赖于半径和Ca2+泵率,产生钙释放的阈值在有限区间内随半径增大而增大.此结果有助于了解细胞内的内质网以及Ca2+泵在细胞Ca2+动力学上的作用. |
| 关 键 词： | Fire-Diffuse-Fire模型 钙波 钙释放 |
| 收稿时间： | 2008-05-29 |
Fire-Diffuse-Fire Calcium Waves in Cylindrical Intracellular Spaces |
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| CHENG Yu,SHI Xiao-min,YU Hong-wang,ZHENG Yu-fan.Fire-Diffuse-Fire Calcium Waves in Cylindrical Intracellular Spaces[J].Journal of Shanghai University(Natural Science),2010,16(1):68-74. | |
| Authors: | CHENG Yu SHI Xiao-min YU Hong-wang ZHENG Yu-fan |
| Institution: | CHENG Yu1,SHI Xiao-min2,YU Hong-wang1,ZHENG Yu-fan1,3 (1.College of Sciences,Shanghai University,Shanghai 200444,China,2.Institute of Systems Science,3.Department of Mathematics,East China Normal University,Shanghai 200062,China) |
| Abstract: | Propagation of fire-diffuse-fire Ca2+ waves through a cylindric domain is considered.Ca2+ concentration is an analytic solution derived from the diffusion equation in the domain.Existence and stability are shown to be dependent on the radius and the Ca2+ pump rate.It is also shown that the threshold of fire increase as radius increasing in finite interval.The results provides better understanding about the roles of endoplasmic and Ca2+ pumps in the intracellular Ca2+ dynamics of cells. |
| Keywords: | fire-diffuse-fire model Ca~(2+) waves calcium release |
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