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岩白菜素缓释片祛痰平喘作用的实验研究
引用本文:刘晓波,方春生,王成军.岩白菜素缓释片祛痰平喘作用的实验研究[J].大理学院学报,2008,7(4):5-6.
作者姓名:刘晓波  方春生  王成军
作者单位:大理学院药学院 云南大理671000
基金项目:云南省大理州科技局资助项目
摘    要:目的:研究岩白菜素缓释片祛痰平喘作用。方法:选用小鼠酚红排泄法、“组胺/乙酰胆碱”致豚鼠哮喘法进行实验。结果:岩白菜素缓释片能显著促进小鼠呼吸道酚红排泄(P〈0.05,P〈0.01);能延迟组胺和乙酰胆碱所致小鼠的引喘潜伏期(P〈0.001)。结论:岩白菜素缓释片具有明显的祛痰平喘作用。

关 键 词:岩白菜素缓释片  祛痰  平喘
文章编号:1672-2345(2008)04-0005-02
修稿时间:2007年12月21

Study Expectorant and Antiasthmatic Action of Sustained Release Tablets of Bergenin
LIU Xiao-bo,FANG Chun-sheng,WANG Cheng-jun.Study Expectorant and Antiasthmatic Action of Sustained Release Tablets of Bergenin[J].Journal of Dali University,2008,7(4):5-6.
Authors:LIU Xiao-bo  FANG Chun-sheng  WANG Cheng-jun
Institution:(Department of Pharmacology, Dali University, Dali, Yunnan 671000, China)
Abstract:Objective:To investigate the pharmacological effects of expectorant and antiasthmatic action of sustained release tablets of Bergenin.Methods:Expectorant experiments with phenol red excretion method in mice,and experimental asthma model on guinea pigs were induced by histamine and acetylcholine in vivo.Result:Sustained release tablets of Bergenin could increase the secretion of phenolphthalein in trachea of mice(P<0.05,P<0.01),and prolong the incubation period of cough which caused by release acetylcholine-histamine in mice(P<0.001).Conclusion:Sustained tablets of Bergenin has significant effects on expectorant and antiasthmatic action.
Keywords:sustained release tablets of Bergenin  expectoran  antiasthmatic
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