Inhibition of thiamine transport in baker's yeast by methylene blue |
| |
Authors: | A Iwashima H Nishimura H Nishino |
| |
Institution: | (1) Department of Biochemistry, Kyoto Prefectural University of Medicine, Kamikyoku, Kyoto, (Japan) |
| |
Abstract: | Summary Methylene blue was found to inhibit thiamine transport competitively (Ki=0.63 M) in baker's yeast. The dye was also effective in abolishing the growth inhibition ofSaccharomyces cerevisiae by pyrithiamine which is known to be taken up by a common transport system for thiamine in yeast cells. A possible mechanism for the inhibition by methylene blue of the thiamine transport system in baker's yeast is discussed. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |