| 胎源微嵌合的研究进展 |
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| 引用本文： | 马腾,刘岩,李海静,郝海生,杜卫华,赵学明,王栋,秦彤,朱化彬.胎源微嵌合的研究进展[J].实验动物科学,2012,29(5):55-59. |
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| 作者姓名： | 马腾 刘岩 李海静 郝海生 杜卫华 赵学明 王栋 秦彤 朱化彬 |
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| 作者单位： | 1. 中国农业科学院北京畜牧兽医研究所,北京100193;甘肃农业大学,兰州730070
2. 中国农业科学院北京畜牧兽医研究所,北京,100193 |
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| 基金项目： | 国家奶牛产业技术体系项目(No.nycytx-10)基本科研业务费资助 |
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| 摘 要： | 母体妊娠期间胎儿细胞通过胎盘进入母体形成胎源微嵌合,在母体中以这种特殊状态存在的胎源物质一直备受关注,这也引发了一场关于胎源微嵌合对母体健康利弊的讨论。本文拟从胎源微嵌合的分布、存在形式、动力学变化及其对母体的影响和临床应用等方面做一综述。
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| 关 键 词： | 胎源微嵌合 动力学变化 自身免疫 组织修复 无创产前检查 |
Progress of Research on Fetal Microchimerism |
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| MA Teng
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LIU Yan
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LI Hai-jing
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HAO Hai-sheng
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DU Wei-hua
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ZHAO Xue-ming
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WANG Dong
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QIN Tong
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ZHU Hua-bin.Progress of Research on Fetal Microchimerism[J].Shiyan Dongwu Kexue,2012,29(5):55-59. |
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| Authors: | MA Teng LIU Yan LI Hai-jing HAO Hai-sheng DU Wei-hua ZHAO Xue-ming WANG Dong QIN Tong ZHU Hua-bin |
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| Institution: | 1(1.Institute of Animal Science,The Chinese Academy of Agricultural Sciences,Beijing 100193,China)(2.Gansu Agricultural University,Lanzhou 730070,China) |
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| Abstract: | Fetal cells accessed to the maternal circulation through the placenta so that formed the fetal microchimerism. Fetal materials in maternal body existed as fetal microchimerism which have been highly concerned. A discussion of fetal microchimerism considering benefits and risks on maternal health were open up. So that related topics on fetal microchimerism were reviewed in this article which include the following main aspects： distribution characteristics, existing forms, dynamics, effect of maternal health and clinical application. |
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| Keywords: | fetal microchimerism dynamics autoimmunity tissue repair non-invasive antenatal examination |
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