5-木糖酯类衍生物的合成及其卷烟加香应用

 为了开发新型烟用香料，将各种挥发性香味酸做成糖酯添加到卷烟中，并对其卷烟加香效果进行评价。本文以1，2-O-丙叉基-?琢-D-呋喃木糖和一系列具有香味的有机酸为原料，无水碳酸钠和4-二甲氨基吡啶（4-DMAP）为催化剂，N，N'-二环己基碳二亚胺（DCC）为缩合剂，经过酯化反应合成出15种5-木糖酯类衍生物，其中13种化合物为新化合物。所有化合物结构均经IR、1H NMR、MS和元素分析得到确证。该15种化合物的卷烟加香实验结果表明，加入各糖酯前体的卷烟评吸结果与对照卷烟相比，均可使香气质改善，香气量增加，达到烟香协调、余味净化、杂气减轻的效果。故合成的5-木糖酯可以作为香原料应用到卷烟中。。

Synthesis of 5-xylose Ester Derivatives and Their Application in Cigarette Flavoring

In order to develop new cigarette flavors, a sensory evaluation is made of cigarettes added with sugar esters, synthesised with some volatilizable organic acids with flavors. Taking 1,2-O-propylidene- -D-furan xylose and a series of organic acids with flavors as raw materials, exsiccated sodium carbonate and 4-dimethylaminopyridine (4-DMAP) as catalyst, N,N'-dicyclohexyl carbodiimide (DCC) as condensing agent, through the esterification, 15 kinds of 5-xylose ester derivatives were synthesized in which 13 compounds were new ones. All the structures of the compounds were confirmed by IR, 1H NMR, MS spectra and elemental analysis. The results of tobacco flavoring experiments of these 15 kinds of compounds show that, compared with cigarette control group, adding sugar esters precursor into cigarettes could improve the aroma quality, increase the aroma quantity, harmonize the aroma, clean the after-taste and reduce offensive odor of cigarettes. It is concluded that the synthesised 5-xylose seter derivatives could be used as flavor materials in cigarette flavoring.