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Increased incidence of lymphomas in survivors of the host-versus-graft syndrome
Authors:E A Cornelius
Institution:(1) Section of Nuclear Medicine, Department of Diagnostic Radiology, Yale Medical School, 333 Cedar Street, 06510 New Haven, CT, USA
Abstract:Summary When (SB)F1 spleen cells were injected into perinatal parental B strain mice a lethal runting syndrome was induced. The survivors showed a significantly increased incidence of lymphomas in old age. the tumors occurred much later and less frequently than in the reverse reaction, Brarr(SB)F1 GVHD.Supported by U.S.P.H.S. grant No. 15,500.
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