| The SARD variety of multifractality of ventricular epicardial mapping during ischemia |
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| 引用本文： | CHEN Ying Martyn P. Nash NING Xinbao WANG Yelin David J. Paterson WANG Jun. The SARD variety of multifractality of ventricular epicardial mapping during ischemia[J]. 科学通报(英文版), 2006, 51(7): 809-814. DOI: 10.1007/s11434-006-0809-x |
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| 作者姓名： | CHEN Ying Martyn P. Nash NING Xinbao WANG Yelin David J. Paterson WANG Jun |
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| 作者单位： | [1]State Key Laboratory of Modern Acoustics, Institute for Biomedical Electronical Engineering, Nanjing University, Nanjing 210093, China [2]Engineering Science and Bioengineering Institute, University of Auckland, Private Bag 92019, NZ [3]Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX13PT, UK |
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| 基金项目： | Experimental work was supported by the Wellcome Trust and British Heart Foundation. This work was supported by the National Natural Science Foundation of China （Grant No. 60501003）. |
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| 摘 要： | Myocardial ischemia creates abnormal electro- physiological substrates that can result in life-threat- ening ventricular arrhythmias. In order to investigate the relation between ischemia and variability of multi- fractality, ventricular epicardial electr…
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| 关 键 词： | 局部缺血 SARD 非线性 基因定位 室性心外膜 |
| 文章编号： | 10.1007/s11434-006-0809-x |
| 收稿时间： | 2005-02-22 |
| 修稿时间： | 2005-02-222006-06-21 |
The SARD variety of multifractality of ventricular epicardial mapping during ischemia |
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| Ying Chen,Martyn P. Nash,Xinbao Ning,Yelin Wang,David J. Paterson,Jun Wang. The SARD variety of multifractality of ventricular epicardial mapping during ischemia[J]. Chinese science bulletin, 2006, 51(7): 809-814. DOI: 10.1007/s11434-006-0809-x |
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| Authors: | Ying Chen Martyn P. Nash Xinbao Ning Yelin Wang David J. Paterson Jun Wang |
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| Affiliation: | (1) State Key Laboratory of Modern Acoustics, Institute for Biomedical Electronical Engineering, Nanjing University, Nanjing, 210093, China;(2) Engineering Science and Bioengineering Institute, University of, Auckland, Private Bag 92019, NZ;(3) Laboratory of Physiology, University of Oxford, Parks Road, Oxford, OX13PT, UK |
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| Abstract: | We have analyzed cardiac ische- mia-reperfusion in an animal model using epicardial electropotential mapping. We investigated the rela- tionship between ischemia and variability of multi- fractality in epicardial electrograms. We present a new parameter called the singularity spectrum area reference dispersion (SARD) that clearly demon- strates the change in multifractility with the extent of myocardiaischemia. By contrasting the 3D ventricular epicardial SARD map with the activation map, we conclude that myocardial ischemia significantly in- fluences the variety of multifractality of ventricular epicardium electrograms and the SARD parameter is useful in correlating multifractality of epicardial elec- trograms with location of ischemia closely. |
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| Keywords: | nonlinearity multifractality mapping ischemia. |
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