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甘利欣治疗抗结核药药物性肝炎的临床观察
引用本文:王萍,吴立红.甘利欣治疗抗结核药药物性肝炎的临床观察[J].内蒙古民族大学学报(自然科学版),2009,24(6):699-700.
作者姓名:王萍  吴立红
作者单位:1. 通辽市传染病医院,内蒙古,通辽,028000
2. 通辽市农村改水与卫生项目办公室,内蒙古,通辽,028000
摘    要:目的:观察甘利欣治疗抗结核药药物性肝炎的临床疗效.方法:将48例抗结核药引起的药物性肝炎患者随机分成治疗组27例和对照组21例.治疗组给予甘利欣治疗4周,对照组给予能量合剂治疗4周,观察治疗前后临床症状和血生化指标的变化.结果:治疗组患者的临床症状和肝功能改善情况显著优于对照组(P〈0.05).结论:甘利欣有很好的保肝、降酶作用,未见不良反应.

关 键 词:药物性肝炎  抗结核药  甘利欣  治疗

Clinical Observation of Diammonium Glycyrrhizinate in the Treatment of Drug-induced Hepatitis Causeded by Antituberculosis Drugs
WANG ping,WU Li-hong.Clinical Observation of Diammonium Glycyrrhizinate in the Treatment of Drug-induced Hepatitis Causeded by Antituberculosis Drugs[J].Journal of Inner Mongolia University for the Nationalities(Natural Sciences),2009,24(6):699-700.
Authors:WANG ping  WU Li-hong
Institution:WANG Ping, WU Li-hong ( 1.Tongliao Infections Hospital, Tongliao 028000, China ; 2.Tongliao Water Renovation and Sanitation Office,Tongliao 028000,China)
Abstract:Objective: To observe the clinical efficacy of diammonium glycyrrhizinate in the treatment of drug-induced hepatitis caused by antiantituberculosis drugs. Methods: 48 patients with drug-induced hepatitis caused by antiantituberculosis drugs were randomly divided into treatment group (27 cases) and control group (21 cases).Treatment group was treated with diammonium glycyrrhizinate for 4 weeks, control group was given energy mixture for 4 weeks, observing the changes of clinical symptoms and biochemical indexes before and after treatment. Results: The clinical symptoms and liver function improvement of treatment group were much better than control group(P〈0.05). Conclusion: Diammonium glycyrrhizinate has a good liver protection and enzyme decreasing role, its adverse reactions are not found.
Keywords:Grug-indueed hepatitis  Antiantitubereulosis drugs  Diammonium glycyrrhizinate  Treatment
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