首页 | 本学科首页   官方微博 | 高级检索  
     


Drug metabolism in spontaneously diabetic guinea pigs
Authors:D. E. Cook  J. D. Jackson  M. R. Past  C. M. Lang  L. P. Bullock
Affiliation:(1) Department of Biochemistry, College of Medicine, University of Nebraska Medical Center, 68105 Omaha, NE, USA;(2) Present address: Department of Comparative Medicine, College of Medicine, Milton S. Hershey Medical Center, 17033 Hershey, PA, USA;(3) Present address: Department of Biochemistry, University of Nebraska College of Medicine, 68105 Omaha, NE;(4) Present address: Department of Biochemistry, Armed Forces Radiobiology Research Institute, 20814 Bethesda, MD;(5) Present address: Department of Medicine, School of Veterinary Medicine, Tufts University, 02130 Jamaica Plain, MA
Abstract:Summary Both sexes of spontaneously diabetic guinea pigs exhibit hyperinsulinemia (>4-fold normal). This diabetic state is associated with the inhibition of hepatic drug metabolism in males but not females.Supported in part by NIH Grants AM 21282 from the NIAMDD and RR00469 from the DRR
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号