15-Hydroxyprostaglandin dehydrogenase and hexokinase in spontaneously hypertensive rat kidney |
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| Authors: | C N Corder K J Bixenstine A P Shapiro W Riehl |
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| Institution: | (1) Departments of Pharmacology and Medicine, School of Medicine, University of Pittsburgh, 15261 Pittsburgh, Pennsylvania, USA |
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| Abstract: | Summary 15-Hydroxyprostaglandin dehydrogenase (PGDH) surged in hypertensive (SHR) and normotensive (WKY) rat kidney at 8 days of age, is greatest in SHR. Hexokinase fell in SHR at 17 days of age, but thereafter was similar to WKY. This suggests multisystem enzymatic abnormalities in SHR kidney during development of hypertension. |
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| Keywords: | Rat kidney hypertensive prostaglandin dehydrogenase hexokinase |
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