Distal axonopathy in streptozotocin diabetes in rats |
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Authors: | S Chokroverty D Seiden P Navidad R Cody |
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Institution: | Neurology Service, VA Medical Center, Lyons, New Jersey 07939. |
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Abstract: | We noted the earliest morphological changes in the motor endplates 8 weeks after the induction of streptozotocin diabetes in rats. Morphometric measurements showed reduced axonal areas of the lateral plantar and the sciatic nerves in the diabetic rats 28 but not 2 and 8 weeks after the experiment. These findings suggested distal axonopathy. |
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