| 选择性保护的萘烷酮的合成 |
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| 引用本文： | 吴雄宇,陈荣礼.选择性保护的萘烷酮的合成[J].中山大学学报(自然科学版),1999,38(6):113-115. |
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| 作者姓名： | 吴雄宇 陈荣礼 |
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| 作者单位： | 中山大学化学与化学工程学院!广州510275(吴雄宇，林永成)，香港理工大学ABCT系!香港(陈荣礼) |
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| 基金项目： | 香港理工大学基金，中山大学化学化工学院马灿安奖学金资助项目 |
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| 摘 要： | 报道了从1,3环己二酮出发,通过硅胶辅助与丁烯酮进行Michael共轭加成生成2(3氧)丁基1,3环己二酮,该化合物在苯中于回流温度下与苄胺缩合并环化生成了6苄氨基3,4,7,8六氢萘1(2H)酮,再用5%的盐酸水溶液于室温下水解,水解产物与乙二醇在对甲苯磺酸催化下反应得到萜类化合物合成的中间体选择性保护的萘烷酮,总收率约18%.
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| 关 键 词： | 1 3-环己二酮 萘烷酮 |
Synthesis of Selectively Protected Decalone |
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| WU Xiong yu,LIN Yong cheng,CHAN Wing lai.Synthesis of Selectively Protected Decalone[J].Acta Scientiarum Naturalium Universitatis Sunyatseni,1999,38(6):113-115. |
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| Authors: | WU Xiong yu LIN Yong cheng CHAN Wing lai |
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| Abstract: | On the surface of silica gel the Michael addition of 1,3 cyclodione to methyl vinyl ketone was accomplished efficiently The product 2 (3 oxo) butyl 1,3 cyclodione was treated with benzylamine to form dienaminone Then hydrolyzed by 5% HCl aqueous solution and reacted with ethylene glycol/toluene sulfonic acid to give the title compound, which is a medium compound in the synthesis of terpenes |
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| Keywords: | cyclodione decalone |
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