Experimentelle Untersuchungen zur Pathogenese des Kontaktekzems

Summary The mechanism of development of contact eczema, which might serve as a working hypothesis for other clinical forms of eczema, is not yet fully understood. An attempt was made, by means of sensitization with Dinitrochlorobenzol in guinea-pigs, to determine the time and place of the pathogenetic phenomena, as well as the organs and tissues affected. Experiments on skin-explants permitted the separate investigation of the different systems, i.e. the blood, nerve and lymphe, presumed to be involved.It was ascertained that the lymphatic system is absolutely essential for the development of sensitization, and the blood path for its generalized spread.

---

---

Ausführliche Publikation erscheint demnächst in Dermatologica, Basel.