Contraction of the large conductance coronary artery produced by acetylcholine in the mini pig |
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Authors: | M Nakazawa K Takeda Y Nakagawa S Imai |
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Institution: | (1) Department of Pharmacology, Niigata University School of Medicine, 951 Niigata, Japan |
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Abstract: | Summary In the mini pig, acetylcholine reduced the coronary blood flow and constricted the large coronary artery. These effects were abolished by atropine, but not by phentolamine, suggesting that cholinergic mechanisms may be involved in coronary artery vasoconstriction. |
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