| 镁及镁合金植入性医疗器械的应用研究进展 |
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| 引用本文： | 吴戍戌,王守仁,刘文涛. 镁及镁合金植入性医疗器械的应用研究进展[J]. 山东科学, 2018, 31(2): 36-44. DOI: 10.3976/j.issn.1002-4026.2018.02.007 |
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| 作者姓名： | 吴戍戌 王守仁 刘文涛 |
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| 作者单位： | 济南大学机械工程学院，山东 济南 250022 |
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| 基金项目： | 国家自然科学基金（51372101，51405195）；山东省泰山学者工程专项经费（2016-2020） |
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| 摘 要： | 镁及镁合金作为生物医用材料具有优异的力学性能和生物相容性，可自主完全降解，而且资源丰富、易于加工成型。本文综述了镁及镁合金植入性医疗器械在骨科和心血管领域的应用现状和最新研究进展，认为目前在临床存在的主要问题是体内耐腐蚀性较差和降解速度未得到有效的控制，未来应向提高耐腐蚀性、控制降解速度等方面发展，有望在临床上得到更广泛的应用。
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| 关 键 词： | 镁合金 植入性医疗器械 镁 可降解 |
| 收稿时间： | 2017-12-24 |
Review on the applications of magnesium and magnesium alloy in implanted medical devices |
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| WU Shu-xu,WANG Shou-ren,LIU Wen-tao. Review on the applications of magnesium and magnesium alloy in implanted medical devices[J]. Shandong Science, 2018, 31(2): 36-44. DOI: 10.3976/j.issn.1002-4026.2018.02.007 |
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| Authors: | WU Shu-xu WANG Shou-ren LIU Wen-tao |
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| Affiliation: | School of Mechanical Engineering, University of Jinan, Jinan 250022, China |
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| Abstract: | As biomedical materials, magnesium and magnesium alloy has advantages of excellent mechanical properties and biological compatibility, completely self degradation, rich in resources, and easy to process molding. Its application status quo and latest research advances in the field of orthopedics and cardiovascular were surveyed in this paper. It is considered that the main problems of magnesium and magnesium alloy implanted medical devices are the poor corrosion resistance in vivo and the failure to control the rate of degradation effectively. Therefore, it should be developed in the future to improve its corrosion resistance and control the rate of degradation，which is expected to be more widely used in clinical practice. |
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| Keywords: | magnesium implantable medical devices biodegradable magnesium alloy |
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