Cytoskeletal filaments of heart conducting system localized by antibody against a 55,000 dalton protein. |
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Authors: | A Eriksson L E Thornell T Stigbrand |
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Abstract: | Cow heart conducting cells characteristically contain cytoplasmic intermediate-sized filaments. We report here the preparation of a specific antibody to a 55,000 dalton protein of isolated cow Purkinje fibres. Confirmation has been obtained that these filaments consist of the 55,000 dalton protein, using the indirect immunofluorescence technique. Cross-reaction is seen with vascular endothelium and smooth muscle cells of various origin, suggesting close identity of different types of intermediate-sized filaments. |
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