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In vitro malignant transformation of hamster lung cells by 2-chlorobutadiene]
Authors:S Menezes  D Papadopoulo  S Lévy  P Markovits
Abstract:Normal Hamster lung cells from an established line were treated with 1-500 microgram . ml-1 2-chlorobutadiene. Those treated with 1 microgram . ml-1 of the compound showed malignant transformations 14 weeks after treatment. The treatment with higher concentrations did not accelerate the transformation process.
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