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Suppression by the cyclohexanetrione Ro 31-0521 of retinoic acid-induced teratogenicity |
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| Authors: | A Kistler |
| Abstract: | The cyclohexanetrione Ro 31-0521, which stimulates prostaglandin synthesis, inhibited retinoic acid-induced cartilage degradation in vitro and suppressed the congenital forelimb malformations in rats treated with retinoic acid on day 13 of gestation in a dose-dependent manner. |
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