| The Reconstructing of Low Signal—noise Ratio Single Ion Channel Signal from Patech—clamp Recordings Sampled in the COlored Background Noise |
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| 引用本文： | 韩晓东 LiuXiangming 等.The Reconstructing of Low Signal—noise Ratio Single Ion Channel Signal from Patech—clamp Recordings Sampled in the COlored Background Noise[J].高技术通讯(英文版),2002,8(3):72-77. |
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| 作者姓名： | 韩晓东 LiuXiangming |
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| 作者单位： | InsitituteofBiomedicalEngineering,HuazhongUniversityofScienceandTechnology,Wuhan430074,P.R.China |
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| 摘 要： | The single ion channel signal is an ionic current that can be recorded by the patch clamp technique,Hidden Markov model(HMM) algorithm has been used to convert the low signal-noise ratio(SNR) noisy recording into an idealized quantal one in the case of white background noise,The Traditional HMM algorithm is extended and adapted to the colored background noise.A new algorithm called EHMM(Extended HMM) algorithm is propsed,and mainly validated by simulation,Resultes show that it‘s effective.
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| 关 键 词： | 噪声 低信号－噪声比 单离子波导信号 生物医学工程 |
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