| 羟基喜树碱诱导肺癌细胞凋亡的实验研究 |
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| 引用本文： | 魏文科. 羟基喜树碱诱导肺癌细胞凋亡的实验研究[J]. 湖北民族学院学报(自然科学版), 2005, 23(4): 369-371 |
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| 作者姓名： | 魏文科 |
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| 作者单位： | 湖北民族学院医学院,湖北恩施445000 |
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| 基金项目： | 湖北省教育厅重点资助项目（2001A08009）. |
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| 摘 要： | 通过设计不同浓度的羟基喜树碱（HCPT）处理体外培养的肺癌细胞,采用形态学与生化特征的观察及流式细胞仪进行检测.实验结果显示：羟基喜树碱（HCPT）能诱导肺癌细胞发生凋亡,且这种凋亡的作用与HCPT的浓度和作用时间有关.
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| 关 键 词： | 羟基喜树碱 细胞凋亡 肺癌 诱导 |
| 文章编号： | 1008-8423（2005）04-0369-03 |
| 收稿时间： | 2005-07-01 |
| 修稿时间： | 2005-07-01 |
Experimental Study on Lung Cancer Cell Death Induced by Hydroxylcamptothecine |
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| WEI Wen-ke. Experimental Study on Lung Cancer Cell Death Induced by Hydroxylcamptothecine[J]. Journal of Hubei Institute for Nationalities(Natural Sciences), 2005, 23(4): 369-371 |
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| Authors: | WEI Wen-ke |
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| Affiliation: | School of Medicine, Hubei Institute for Nationalities, Enshi 445000, China |
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| Abstract: | Through study on HCPT apoptosis - inducing action on externally - cultured lung cancer cell, HCPT with different concentrations are designed to deal with externally - cultured lung cancer cells, which are inspected throngh morphology and biochemistry and examined with flow cytometry (FCM) . The experiment shows: different experiments show that HCPT can really induce apoptosis to lung cancer cell, which is affected by the concentration of HCPT and by the time of action and basis is provided for lung cancer treatment. |
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| Keywords: | hydroxylcamptothecine (HCPT) cell apoptosis lung cancer induction |
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