干燥环境下爆炸伤的细菌学变化分析

探讨了干燥环境下爆炸伤细菌定量变化及感染发生．采用三元品种猪制作干燥环境下的爆炸伤模型，对伤后4h、7h、9h、12h、16h、24h、48h进行创面观察、血中白细胞计数、细菌计数、细菌鉴定及药敏测定分析．其结果表明：爆炸伤后24h创面细菌数量可达（5．64＋0．20）×10^6／g组织，白细胞数可达（23．43＋3．93）×10^9／L，创面组织出现炎症症状，清创后每克组织细菌数量增加速度减慢．爆炸伤创面细菌种类多，细菌对青霉素、四环素、红霉素及复方新诺明表现耐药性，对三代头孢菌类和喹诺酮类药物敏感．干燥环境下爆炸伤的清创时间可适当延长，可在伤后16h内进行清创．

Analysis of the Changes of Bacteria in Explosive Injured Trauma under Dry Environment

Our objective was to study the change in quantity of bacteria and the development of infection in dry environment. Using San-yuan pig to establish the model of explosive injured trauma, the general oh servation and quantitive bacterial analysis were made in line with, kinds of bacteria and antimierobiai suseeptibility. The numerations of leukoeyt of blood were detected at 4 h, 7 h, 9 h, 12 h, 16 h, 24 h, 48 h after injury respectively. It was shown that when injured 24 h, the level of bacteria in trauma tissue was （5. 64 ＋0.20） × 10^6 efu/g, and the numeration of leukoeyt of blood was （23.43＋3.93） × 10^9/L. There was an inflammation symptom in injured trauma. The level of increasing bacteria in trauma tissue decreased after debridement. There were many kinds of bacteria in injured trauma, and they had the resistance to drugs such as benzylpenicillin, economycin, erythromycin and trimoxazole. They were sensitive to antimicrobial drugs like third-generation cephalosporins and quinolone. Our conclusion was that the time of debriderment of explosive injured trauma in dry environment may be delayed until 16 h after injury.