| 高锰酸钾氧化茴脑制备茴香酸的工艺研究 |
| |
| 引用本文： | 殷勇,王立升,洪绍彩,杨华,田娟,段曼.高锰酸钾氧化茴脑制备茴香酸的工艺研究[J].广西大学学报(自然科学版),2012,37(3):421-424. |
| |
| 作者姓名： | 殷勇 王立升 洪绍彩 杨华 田娟 段曼 |
| |
| 作者单位： | 1. 广西大学化学化工学院,广西南宁,530004
2. 中国人民武装警察部队广西总队医院,广西南宁,530003 |
| |
| 基金项目： | 广西自然科学基金重点项目 |
| |
| 摘 要： | 为了有效的利用自然资源,降低生产成本,以茴脑为原料,高锰酸钾做氧化剂,四丁基溴化铵(TBAB)为相转移催化剂,通过氧化合成了茴香酸。结果表明,最佳反应条件为:n(茴脑)∶n(高锰酸钾)∶n(TBAB)=1∶2.2∶0.002,反应温度为85～90℃,反应时间为6 h,产率可达85.8%。产物结构经1HNMR,MS确证。研究结果为工业化生产茴香酸奠定了基础。
|
| 关 键 词： | 茴脑 高锰酸钾 TBAB 茴香酸 相转移催化剂 |
Preparation of p-anisic acid from anethol by potassium permanganate |
| |
| YIN Yong
,
WANG Li-sheng
,
HONG Shao-cai
,
YANG Hua
,
TIAN Juan
,
DUAN Man.Preparation of p-anisic acid from anethol by potassium permanganate[J].Journal of Guangxi University(Natural Science Edition),2012,37(3):421-424. |
| |
| Authors: | YIN Yong WANG Li-sheng HONG Shao-cai YANG Hua TIAN Juan DUAN Man |
| |
| Institution: | 1(1.School of Chemistry and Chemical Engineering,Guangxi University,Nanning 530004,China; 2.Guangxi Provincial Corps Hospital,Chinese People’s Armed Police Forces,Nanning 530003,China) |
| |
| Abstract: | In order to effectively make use of natural resources and reduce the production costs,under the phase transfer catalyst of tetrabutyl ammonium bromide,p-anisic acid was synthesized using anethol as raw material and potassium permanganate as oxidant.The structure of the product was characterized by 1HNMR and MS.The results showed that the optimal conditions were as follows: the molar ratio between anethol,potassium permanganate and TBAB was 1∶ 2.2∶ 0.002,the reaction temperature was 85~90 ℃,reaction time was 6 h,and 85.8% of yield was achieved.The results lay a foundation for the industrial production of p-anisic acid. |
| |
| Keywords: | anethol potassium permanganate TBAB p-anisic acid phase transfer catalyst |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
