Sur les effets du 5-fluoruracile injecté à l'embryon de Poulet à des stades avancés de l'incubation

Summary 5-FU, injected into the chick embryo on the 5th and the 8th day of incubation, has an immediate lethal effect and a later lethal effect which are very attenuated. On the other hand, when injected in very high doses, the substance has a uniform teratogenic action and causes malformations which attain specifically the members, the brain, and the beak.

---

---

Ces recherches ont été faites grâce à un subside du Fonds National Suisse de la recherche scientifique et de la Fondation E. Barell.