A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral,Sinularia sp. |
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| Authors: | T. Shindo A. Sato H. Horikoshi H. Kuwano |
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| Affiliation: | (1) New Lead Research Laboratories, Sankyo Co. Ltd., 2-58, l-chome, Hiromachi, Shinagawa-ku, 140 Tokyo, Japan;(2) Biological Research Laboratories, Sankyo Co. Ltd., 2-58, l-chome, Hiromachi, Shinagawa-ku, 140 Tokyo, Japan;(3) Analytical and Metabolic Research Laboratories, Sankyo Co. Ltd., 2-58, l-chome, Hiromachi, Shinagawa-ku, 140 Tokyo, Japan |
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| Abstract: | Separation of a lipophilic extract of a soft coral,Sinularia sp., assayed by enhancement of glucose transport in rat adipocytes, gave farnesyl 4-O- -D-arabinopyranosyl--D-arabinopyranoside-2,2 ,3-triacetate (1a) whose structure was determined by spectroscopy. Enhancers of glucose transport may be useful for the prevention and treatment of diabetic disorders. |
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| Keywords: | Soft coral Sinularia sp. farnesyl arabinoside glucose transport enhancer diabetic complications |
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