| 新型含异喹啉类酰化转移配体的合成及其表征 |
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| 引用本文： | 周辉,徐青,陈沛然.新型含异喹啉类酰化转移配体的合成及其表征[J].石河子大学学报,2008,26(6). |
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| 作者姓名： | 周辉 徐青 陈沛然 |
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| 作者单位： | 东华大学化学化工与生物工程学院 |
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| 摘 要： | 以1-氯异喹啉为原料,通过硝化反应合成得到1-氯-5-硝基异喹啉;再在二异丙基乙基胺为溶剂,和D-苯苷氨醇反应得到(R)-N-(5-硝基异喹啉-2)-2-羟基-1-苯乙胺;再进一步用二氯亚砜和羟基反应生成离去基团,异喹啉上的氮亲核进攻后成环得到含硝基的异喹啉配体。并对产物进行了核磁共振、红外、质谱表征。所得化合物未见文献报道。
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| 关 键 词： | 异喹啉 氨基醇 配体 合成 表征 |
Synthesis and Analyses of a Series of Novel Acyl Transfer Catalysts Containing Isoquinoline |
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| ZHOU Hui,XU Qing,CHEN Pei-ran.Synthesis and Analyses of a Series of Novel Acyl Transfer Catalysts Containing Isoquinoline[J].Journal of Shihezi University(Natural Science),2008,26(6). |
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| Authors: | ZHOU Hui XU Qing CHEN Pei-ran |
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| Abstract: | 1-chloro-5-nitroisoquinoline was synthesized by nitration from 1-chloroisoquinoline;then,a novel Acyl Transfer Catalysts Containing Isoquinoline were synthesized in two stepsby using D-(-)-phenylglycinol and 1-chloro-5-nitroisoquinoline as starting material.The final products was identified by nuclear magnetic resonance(1H NMR),infrared spectrometry(IR),Mass Spectrometry(MS).The compound has not been reported,being considered as a new compound. |
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| Keywords: | isoquinoline chiral amino alcohols catalysts synthesis analyses |
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